SCHEMBL1104156

SCHEMBL1104156

CCOOc1ccc(NC(=O)C(C)(C)CC)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.47
MEN1 O00255 5/20 0.47
TDP1 Q9NUW8 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 3/20 0.44
POLB P06746 2/20 0.44
CYP1A2 P05177 1/20 0.44
ALDH1A1 P00352 1/20 0.43
PDK1 Q15118 2/20 0.42
PDK2 Q15119 2/20 0.42
PDK3 Q15120 2/20 0.42
PDK4 Q16654 2/20 0.42
HTT P42858 1/20 0.42
S1PR4 O95977 2/20 0.42
S1PR1 P21453 2/20 0.42
S1PR3 Q99500 2/20 0.42
S1PR5 Q9H228 2/20 0.42
TSHR P16473 1/20 0.42
BRD4 O60885 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12863518 0.87 KMT2A (0.43) KMT2AMEN1TDP1L3MBTL1LMNA
SCHEMBL1104128 0.85 GPR174 (0.45) KMT2AMEN1TDP1L3MBTL1LMNA
SCHEMBL12226380 0.83 L3MBTL1 (0.61) KMT2AMEN1TDP1L3MBTL1LMNA
SCHEMBL1104169 0.83 PDK1 (0.60) KMT2AMEN1TDP1L3MBTL1LMNA
SCHEMBL10064131 0.81 KMT2A (0.49) KMT2AMEN1TDP1L3MBTL1LMNA
SCHEMBL14582701 0.80 GAA (0.51) KMT2AMEN1TDP1L3MBTL1LMNA
SCHEMBL12226381 0.79 L3MBTL1 (0.73) KMT2AMEN1TDP1L3MBTL1LMNA
SCHEMBL97686 0.77 MEN1 (0.54) KMT2AMEN1TDP1L3MBTL1LMNA
SCHEMBL13934889 0.77 POLB (0.55) KMT2AMEN1TDP1L3MBTL1LMNA
SCHEMBL12205961 0.76 MEN1 (0.50) KMT2AMEN1TDP1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7883827-B2 acrylate copolymer binder has superior developing properties while suppressing damages resulting from permeation of the developer caused by the acid content; for use with a laser beam; excellent in printing durability and image formation FUJIFILM CORPORATION (JP) 2011-02-08 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed