Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL464802 | 0.86 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2142341 | 0.84 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29087975 | 0.83 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL434075 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28357562 | 0.81 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1014645 | 0.81 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27753211 | 0.81 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27694332 | 0.81 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9744808 | 0.80 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8002867 | 0.80 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116638-A1 | PROSTHESES CONTACT LENSES AND POLYMERS THEREFOR | CONTACT LENSES (MANUFACTURING) LIMITED (GB) | 1984-08-29 | — | — | EP | claimed |
| WO-1984000969-A1 | PROSTHESES CONTACT LENSES AND POLYMERS THEREFOR | CONTACT LENS MFG LTD (GB) | 1984-03-15 | — | — | WO | claimed |
| EP-4208509-B1 | CROSS-LINKABLE COMPOSITIONS BASED ON ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2024-02-28 | — | — | EP | disclosed |
| CN-107987680-B | Water-based epoxy graphene anticorrosive paint | 海洋化工研究院有限公司 | 2020-02-07 | — | — | CN | disclosed |