Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744808 | 0.88 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL434075 | 0.87 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11293539 | 0.85 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL8132195 | 0.83 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2142341 | 0.82 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17417867 | 0.82 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL464802 | 0.81 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29087975 | 0.81 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5732289 | 0.81 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL991469 | 0.80 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152508-A | OXYGEN PERMEABILITY, DIMENSIONAL STABILITY | POLYMER TECHNOLOGY CORPORATION (US) | 1979-05-01 | — | — | US | claimed |
| EP-0972223-A4 | LIGHT FILTERING CONTACT LENS | PARAGON VISION SCIENCES INC (US) | 2000-07-19 | — | — | EP | disclosed |
| EP-0972223-A1 | LIGHT FILTERING CONTACT LENS | PARAGON VISION SCIENCES, INC. (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5923397-A | INTERPENETRATING NETWORK OF CROSSLINKED ACRYLIC POLYMERS; RIGID GAS PERMEABLE CORE SECTION AND SOFT EDGE SECTION ATTACHED ANNULARLY ABOUT THE CORE SECTION; EASIER TO CLEAN, PROVID GREATER VISION ACUITY AND GREATER COMFORT | BAUSCH & LOMB INCORPORATED (US) | 1999-07-13 | — | — | US | disclosed |
| US-5846457-A | Light filtering contact lens method | SPORTSIGHT, LLC | 1998-12-08 | — | — | US | disclosed |
| WO-1998044380-A1 | LIGHT FILTERING CONTACT LENS | PARAGON VISION SCIENCES, INC. (US) | 1998-10-08 | — | — | WO | disclosed |
| US-5617154-A | Light filtering contact lens | FLEXLENS (US) | 1997-04-01 | — | — | US | disclosed |
| EP-0227967-A2 | Imidazoline derivatives, process for preparing same, herbicide containing same, and plant growth regulator containing same | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-07-08 | — | — | EP | disclosed |
| US-4645811-A | Material used for optical devices | OCULUS CONTACT LENS COMPANY (US) | 1987-02-24 | — | — | US | disclosed |
| US-4436730-A | CATIONIC PROTECTIVE COATING FOR CONTACT LENSES | POLYMER TECHNOLOGY CORPORATION (US) | 1984-03-13 | — | — | US | disclosed |
| US-4321261-A | Ionic ophthalmic solutions | POLYMER TECHNOLOGY CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4168112-A | Contact lens with a hydrophilic, polyelectrolyte complex coating and method for forming same | POLYMER TECHNOLOGY CORPORATION (US) | 1979-09-18 | — | — | US | disclosed |