Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8002867 | 0.88 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL434075 | 0.87 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8132195 | 0.83 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17417867 | 0.82 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2142341 | 0.82 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL464802 | 0.81 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL29087975 | 0.81 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5732289 | 0.81 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL991469 | 0.80 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11041704 | 0.80 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9879153-B2 | Anti-icing composite | WANG LIANG (US) | 2018-01-30 | — | — | US | disclosed |
| US-20160009971-A1 | Anti-Icing Composite | WANG LIANG (US) | 2016-01-14 | — | — | US | disclosed |
| US-5084537-A | Contact lenses from organosilicon monomers that are oxygen permeable | BAUSCH & LOMB, INCORPORATED (US) | 1992-01-28 | — | — | US | disclosed |
| US-5002979-A | Hyydrogenorganosilicon monomer, organosilicon, fluoroorgano monomer, a hydrophobic monomer and a crosslinking agent | BAUSCH & LOMB INCORPORATED (US) | 1991-03-26 | — | — | US | disclosed |