Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044101 | 0.88 | GAA (0.48) | SIRT2LMNARAB9ATHRBMEN1 | |
| SCHEMBL11039230 | 0.87 | SIRT2 (0.45) | SIRT2LMNATDP1NR1H4RAB9A | |
| SCHEMBL11037929 | 0.87 | SIRT2 (0.55) | SIRT2LMNATDP1NR1H4RAB9A | |
| SCHEMBL11041569 | 0.87 | HPGD (0.53) | TDP1RAB9AMEN1KMT2A | |
| SCHEMBL9799045 | 0.87 | RAB9A (0.53) | SIRT2NR1H4RAB9AMEN1KMT2A | |
| SCHEMBL11041771 | 0.86 | RAB9A (0.55) | SIRT2TDP1RAB9AMEN1KMT2A | |
| SCHEMBL11043978 | 0.85 | SIRT2 (0.42) | SIRT2LMNATDP1NR1H4RAB9A | |
| SCHEMBL11046557 | 0.85 | PSMB5 (0.48) | SIRT2LMNATHRBMEN1KMT2A | |
| SCHEMBL11038572 | 0.85 | LMNA (0.53) | SIRT2LMNANR1H4THRBMEN1 | |
| SCHEMBL11042909 | 0.85 | MAPT (0.46) | SIRT2LMNATDP1NR1H4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490165-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds, methods for preparing same and herbicidal use thereof | AMERICAN CYANAMID COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| US-4308213-A | Meta-(phenylalkoxy)phenyl-N-methoxy-N-methylurea compounds | AMERICAN CYANAMID COMPANY (US) | 1981-12-29 | — | — | US | disclosed |