Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 3/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17048718 | 0.87 | ALDH1A1 (0.38) | ALDH1A1GAAKDM4EALOX15 | |
| SCHEMBL11040625 | 0.81 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1MAPTHPGD | |
| SCHEMBL29723947 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GAAL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL11147808 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GAAL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL11042586 | 0.80 | ALDH1A1 (0.49) | ALDH1A1GAAL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL11042257 | 0.78 | ALDH1A1 (0.42) | ALDH1A1ACHECA1CA2L3MBTL1 | |
| SCHEMBL11042326 | 0.76 | ALDH1A1 (0.49) | ALDH1A1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL17048984 | 0.75 | HPGD (0.40) | ALDH1A1GAAL3MBTL1SMN1; SMN2KDM4E | |
| SCHEMBL2610141 | 0.74 | ALDH1A1 (0.43) | ALDH1A1NPC1RAB9AGAAL3MBTL1 | |
| SCHEMBL6094021 | 0.74 | CA1 (0.36) | ALDH1A1ACHECA1CA2NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |