Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041797 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPTHPGDL3MBTL1 | |
| SCHEMBL30536243 | 0.75 | ALDH1A1 (0.39) | ALDH1A1MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL11040699 | 0.73 | ALDH1A1 (0.38) | ALDH1A1MEN1USP2MAPTHPGD | |
| SCHEMBL17048718 | 0.73 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL11042164 | 0.72 | MAPT (0.46) | ALDH1A1MEN1MAPTHPGDMAPK1 | |
| SCHEMBL19365963 | 0.72 | ALDH1A1 (0.39) | ALDH1A1MEN1USP2POLBMAPT | |
| SCHEMBL7087812 | 0.72 | SLC6A3 (0.43) | — | |
| SCHEMBL10760181 | 0.72 | — | — | |
| SCHEMBL11041825 | 0.72 | GAA (0.44) | ALDH1A1MAPTKMT2AHTT | |
| SCHEMBL6947251 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MEN1MAPK1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |