SCHEMBL1104185

SCHEMBL1104185

CCC(C)(C)C(=O)Nc1ccc(C(=O)SC)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.47
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
LMNA P02545 3/20 0.44
HTT P42858 2/20 0.44
HDAC1 Q13547 3/20 0.44
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC7 Q8WUI4 2/20 0.44
HDAC2 Q92769 2/20 0.44
HDAC10 Q969S8 2/20 0.44
HDAC11 Q96DB2 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
HDAC9 Q9UKV0 2/20 0.44
HDAC5 Q9UQL6 2/20 0.44
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12226380 0.86 L3MBTL1 (0.61) MEN1KMT2ATDP1L3MBTL1LMNA
SCHEMBL20100978 0.83 MAPT (0.51) MEN1KMT2ATDP1L3MBTL1NPC1
SCHEMBL802226 0.83 EPHX2 (0.54) MEN1KMT2ATDP1L3MBTL1LMNA
SCHEMBL21673452 0.82 SMN1; SMN2 (0.53) MEN1KMT2ATDP1L3MBTL1NPC1
SCHEMBL12226381 0.81 L3MBTL1 (0.73) MEN1KMT2ATDP1L3MBTL1NPC1
SCHEMBL751079 0.81 MEN1 (0.60) MEN1KMT2AL3MBTL1NPC1RAB9A
SCHEMBL13934889 0.80 POLB (0.55) MEN1KMT2ATDP1L3MBTL1NPC1
SCHEMBL97686 0.80 MEN1 (0.54) MEN1KMT2ATDP1L3MBTL1NPC1
SCHEMBL13921981 0.79 MEN1 (0.48) MEN1KMT2ATDP1L3MBTL1RAB9A
SCHEMBL1104194 0.78 MEN1 (0.70) MEN1KMT2ANPC1RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7507525-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-7279539-B2 Alkali-soluble polymer and polymerizable composition thereof FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed