SCHEMBL20100978

SCHEMBL20100978

CCC(C)(C)C(=O)Nc1ccc(C(C)=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
POLB P06746 1/20 0.51
GAA P10253 1/20 0.51
MCL1 Q07820 1/20 0.51
NOX1 Q9Y5S8 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
NPC1 O15118 5/20 0.50
RAB9A P51151 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
ALDH1A1 P00352 2/20 0.49
HTT P42858 3/20 0.49
NLRP1 Q9C000 1/20 0.49
HDAC1 Q13547 2/20 0.48
HPGD P15428 1/20 0.48
MAPK1 P28482 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12226380 0.89 L3MBTL1 (0.61) MAPTMEN1KMT2APOLBGAA
SCHEMBL9094137 0.87 MEN1 (0.69) MAPTMEN1KMT2APOLBGAA
SCHEMBL802226 0.86 EPHX2 (0.54) MEN1KMT2APOLBTDP1L3MBTL1
SCHEMBL1104201 0.85 ALDH1A1 (0.52) MAPTMEN1KMT2AGAATDP1
SCHEMBL21673452 0.85 SMN1; SMN2 (0.53) MAPTMEN1KMT2APOLBTDP1
SCHEMBL12226381 0.84 L3MBTL1 (0.73) MAPTMEN1KMT2APOLBTDP1
SCHEMBL1104185 0.83 MEN1 (0.49) MAPTMEN1KMT2APOLBTDP1
SCHEMBL751079 0.83 MEN1 (0.60) MAPTMEN1KMT2APOLBGAA
SCHEMBL13934889 0.82 POLB (0.55) MEN1KMT2APOLBTDP1NPC1
SCHEMBL97686 0.82 MEN1 (0.54) MAPTMEN1KMT2APOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180117942-A1 PRINTING PLATE PRECURSOR, PLANOGRAPHIC PRINTING PLATE, BLANK PLATE FOR PRINTING, AND LAMINATE THEREOF FUJIFILM CORPORATION (JP) 2018-05-03 US disclosed