SCHEMBL1104201

SCHEMBL1104201

CCC(C)(C)C(=O)Nc1ccc(S(=O)(=O)NC(=O)c2ccc(C(C)=O)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
KMT2A Q03164 3/20 0.52
MAPT P10636 3/20 0.52
MEN1 O00255 2/20 0.52
LMNA P02545 3/20 0.49
KDM4E B2RXH2 1/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B10 Q99714 1/20 0.48
ALOX12 P18054 1/20 0.47
FLT1 P17948 2/20 0.47
FLT4 P35916 2/20 0.47
KDR P35968 2/20 0.47
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
HDAC1 Q13547 1/20 0.46
CA12 O43570 1/20 0.46
HPGD P15428 1/20 0.46
USP2 O75604 1/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14483812 0.89 FLT1 (0.63) KMT2AMAPTMEN1HSD17B10FLT1
SCHEMBL11940946 0.85 SMN1; SMN2 (0.60) ALDH1A1MAPTKDM4EHSD17B10CA1
SCHEMBL20100978 0.85 MAPT (0.51) ALDH1A1KMT2AMAPTMEN1LMNA
SCHEMBL13706541 0.81 CA12 (0.51) ALDH1A1KMT2AMAPTMEN1LMNA
SCHEMBL9923569 0.80 ALDH1A1 (0.51) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL9483252 0.79 KMT2A (0.58) ALDH1A1KMT2AMAPTMEN1LMNA
SCHEMBL13921976 0.78 KMT2A (0.52) ALDH1A1KMT2AMAPTMEN1LMNA
SCHEMBL6361239 0.77 ALDH1A1 (0.54) ALDH1A1KMT2AMAPTMEN1LMNA
SCHEMBL12226380 0.76 L3MBTL1 (0.61) ALDH1A1KMT2AMAPTMEN1LMNA
SCHEMBL1104159 0.76 CA1 (0.71) KMT2ACA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7507525-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-7279539-B2 Alkali-soluble polymer and polymerizable composition thereof FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed