Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043557 | 0.86 | CYP19A1 (0.35) | — | |
| SCHEMBL11044703 | 0.84 | AR (0.31) | — | |
| SCHEMBL11042162 | 0.82 | TOP2A (0.34) | ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11046890 | 0.82 | CYP19A1 (0.36) | MEN1KMT2A | |
| SCHEMBL11045307 | 0.80 | — | — | |
| SCHEMBL11046338 | 0.77 | CYP19A1 (0.37) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11045300 | 0.77 | P2RX7 (0.33) | — | |
| SCHEMBL11050458 | 0.76 | SLC6A2 (0.33) | NPC1ALDH1A1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL11044736 | 0.74 | CYP19A1 (0.41) | NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL11063867 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122452-A1 | Triazolyl- and imidazolyl-substituted fluoroalkane derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-10-24 | — | — | EP | claimed |