Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046338 | 0.89 | CYP19A1 (0.37) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL11043557 | 0.88 | CYP19A1 (0.35) | — | |
| SCHEMBL11044112 | 0.88 | LMNA (0.40) | ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL11046890 | 0.81 | CYP19A1 (0.36) | — | |
| SCHEMBL11045300 | 0.81 | P2RX7 (0.33) | — | |
| SCHEMBL11044703 | 0.80 | AR (0.31) | — | |
| SCHEMBL11042162 | 0.79 | TOP2A (0.34) | ALDH1A1LMNATOP2ARAB9ASMN1; SMN2 | |
| SCHEMBL11046978 | 0.78 | LMNA (0.37) | ALDH1A1LMNAGAASMN1; SMN2 | |
| SCHEMBL11043196 | 0.76 | — | — | |
| SCHEMBL11042268 | 0.76 | MEN1 (0.31) | NPC1ALDH1A1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122452-A1 | Triazolyl- and imidazolyl-substituted fluoroalkane derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-10-24 | — | — | EP | disclosed |