Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043557 | 0.89 | CYP19A1 (0.35) | CYP19A1 | |
| SCHEMBL11050458 | 0.89 | SLC6A2 (0.33) | SMN1; SMN2NPC1RAB9ASLC6A2HTR2A | |
| SCHEMBL11044112 | 0.86 | LMNA (0.40) | KMT2ASMN1; SMN2HTTMAPTCXCR3 | |
| SCHEMBL11044736 | 0.85 | CYP19A1 (0.41) | CYP19A1KMT2ASMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL11046890 | 0.82 | CYP19A1 (0.36) | CYP19A1KMT2ATSHR | |
| SCHEMBL11042162 | 0.80 | TOP2A (0.34) | CYP19A1SMN1; SMN2RAB9A | |
| SCHEMBL11045300 | 0.77 | P2RX7 (0.33) | — | |
| SCHEMBL11042268 | 0.77 | MEN1 (0.31) | KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL11063867 | 0.77 | — | — | |
| SCHEMBL11046978 | 0.76 | LMNA (0.37) | KMT2ASMN1; SMN2L3MBTL1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122452-A1 | Triazolyl- and imidazolyl-substituted fluoroalkane derivatives, process for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1984-10-24 | — | — | EP | disclosed |