Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CAD | P27708 | 2/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL690090 | 0.74 | — | — | |
| SCHEMBL1300246 | 0.74 | — | — | |
| SCHEMBL690089 | 0.74 | — | — | |
| SCHEMBL6950284 | 0.72 | — | — | |
| SCHEMBL16467758 | 0.72 | CAD (0.48) | GAAMAPTEGLN1CYP2D6LMNA | |
| SCHEMBL635259 | 0.68 | — | — | |
| SCHEMBL1702706 | 0.68 | EGLN1 (0.36) | GAAMAPTEGLN1CYP2D6LMNA | |
| SCHEMBL5069018 | 0.67 | — | — | |
| SCHEMBL7851817 | 0.65 | — | — | |
| Dihydroorotate SCHEMBL758070 | 0.65 | CAD (0.43) | GAAMAPTEGLN1CYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0119995-A1 | NEW ACYLATED DERIVATIVES OF DEHYDRO OROTIC ACID, PREPARATIONS THEREOF AND UTILIZATIONS THEREOF AS DRUG | CORBIERE, Jérôme (FR) | 1984-10-03 | — | — | EP | claimed |
| WO-1984001385-A1 | NEW ACYLATED DERIVATIVES OF DEHYDRO OROTIC ACID, PREPARATIONS THEREOF AND UTILIZATIONS THEREOF AS DRUG | CORBIERE JEROME | 1984-04-12 | — | — | WO | claimed |
| EP-0119995-A1 | NEW ACYLATED DERIVATIVES OF DEHYDRO OROTIC ACID, PREPARATIONS THEREOF AND UTILIZATIONS THEREOF AS DRUG | CORBIERE, Jérôme (FR) | 1984-10-03 | — | — | EP | disclosed |
| WO-1984001385-A1 | NEW ACYLATED DERIVATIVES OF DEHYDRO OROTIC ACID, PREPARATIONS THEREOF AND UTILIZATIONS THEREOF AS DRUG | CORBIERE JEROME | 1984-04-12 | — | — | WO | disclosed |