⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31453550 | 0.79 | — | — | |
| SCHEMBL29955605 | 0.77 | CYP2D6 (0.37) | — | |
| SCHEMBL690089 | 0.77 | — | — | |
| SCHEMBL1300246 | 0.77 | — | — | |
| SCHEMBL690090 | 0.77 | — | — | |
| SCHEMBL6950284 | 0.75 | — | — | |
| SCHEMBL16467758 | 0.75 | CAD (0.48) | — | |
| SCHEMBL11042375 | 0.68 | GAA (0.40) | — | |
| Dihydroorotate SCHEMBL758070 | 0.68 | CAD (0.43) | — | |
| SCHEMBL6346374 | 0.68 | EGLN1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102649777-B | Method of preparing 1-aryl-3 carboxyl-5-pyrazolone compound | SINOCHEM CORP | 2014-03-12 | — | — | CN | claimed |
| CN-102649777-A | Method of preparing 1-aryl-3 carboxyl-5-pyrazolone compound | SINOCHEM CORP | 2012-08-29 | — | — | CN | claimed |
| CN-116234444-A | Mixtures with insecticidal activity comprising sulfur-containing heterocyclylalkoxy compounds, oxides or salts thereof | 皮埃企业有限公司 | 2023-06-06 | — | — | CN | disclosed |
| EP-2254858-B1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | DU PONT (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2231592-B1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | DU PONT (US) | 2016-02-17 | — | — | EP | disclosed |
| US-9162973-B2 | Method for preparing 2-aminobenzamide derivatives | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-10-20 | — | — | US | disclosed |
| EP-2668153-B1 | METHOD FOR PREPARING 2-AMINOBENZAMIDE DERIVATIVES | DU PONT (US) | 2015-03-04 | — | — | EP | disclosed |
| US-20150005503-A1 | METHOD FOR PREPARING 2-AMINOBENZAMIDE DERIVATIVES | FMC CORPORATION | 2015-01-01 | — | — | US | disclosed |
| US-8871939-B2 | Method for preparing 2-aminobenzamide derivatives | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-10-28 | — | — | US | disclosed |
| CN-101855202-B | Process for preparing 2-amino-5-cyanobenzoic acid derivatives | DU PONT | 2014-06-25 | — | — | CN | disclosed |
| US-8748630-B2 | Process for preparing 2-amino-5-cyanobenzoic acid derivatives | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-06-10 | — | — | US | disclosed |
| EP-2102150-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2009111553-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-09-11 | — | — | WO | disclosed |
| EP-2094644-A2 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. Du Pont de Nemours and Company (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2009085816-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009061991-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-05-14 | — | — | WO | disclosed |
| WO-2009006061-A2 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-01-08 | — | — | WO | disclosed |
| WO-2008082502-A2 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008070158-A1 | PROCESS FOR PREPARING 2-AMINO-5-CYANOBENZOIC ACID DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-06-12 | — | — | WO | disclosed |
| US-4220791-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-09-02 | — | — | US | disclosed |