Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24722331 | 0.86 | MEN1 (0.55) | MEN1KMT2AMAPK1POLBSMN1; SMN2 | |
| SCHEMBL5841291 | 0.84 | MEN1 (0.53) | MEN1KMT2AMAPK1POLBSMN1; SMN2 | |
| SCHEMBL7834034 | 0.84 | MEN1 (0.56) | MEN1KMT2AMAPK1POLBSMN1; SMN2 | |
| SCHEMBL9828028 | 0.83 | MEN1 (0.62) | MEN1KMT2AMAPK1POLBSMN1; SMN2 | |
| SCHEMBL7835759 | 0.82 | MEN1 (0.58) | MEN1KMT2AMAPK1POLBSMN1; SMN2 | |
| SCHEMBL7633512 | 0.81 | SMN1; SMN2 (0.46) | MEN1KMT2AMAPK1POLBSMN1; SMN2 | |
| SCHEMBL9117986 | 0.81 | CTNNB1 (0.63) | POLBALDH1A1KDM4ECYP3A4 | |
| SCHEMBL10789717 | 0.81 | KMT2A (0.53) | MEN1KMT2AMAPK1POLBSMN1; SMN2 | |
| SCHEMBL6628602 | 0.81 | POLB (0.61) | MEN1KMT2AMAPK1POLBSMN1; SMN2 | |
| SCHEMBL8507477 | 0.81 | MEN1 (0.53) | MEN1KMT2AMAPK1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |