Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834034 | 0.98 | MEN1 (0.56) | MEN1KMT2AALDH1A1KDM4ETHRA | |
| SCHEMBL7835759 | 0.93 | MEN1 (0.58) | MEN1KMT2AALDH1A1KDM4ETHRA | |
| SCHEMBL7837299 | 0.86 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1KDM4EMAPK1 | |
| SCHEMBL11042463 | 0.86 | MEN1 (0.51) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL5841291 | 0.85 | MEN1 (0.53) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL9828028 | 0.84 | MEN1 (0.62) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL9588048 | 0.83 | THRA (0.66) | THRATHRBHSD17B3 | |
| SCHEMBL29178467 | 0.83 | THRA (0.49) | MEN1KMT2ATHRATHRBHSD17B3 | |
| SCHEMBL6628602 | 0.82 | POLB (0.61) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL8507477 | 0.82 | MEN1 (0.53) | MEN1KMT2AALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251191-A1 | ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2022-12-01 | — | — | WO | disclosed |