Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | NFKBIA | P25963 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657559 | 0.84 | F2 (0.59) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL22531716 | 0.79 | KMT2A (0.52) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL29549101 | 0.79 | KMT2A (0.52) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL29549435 | 0.78 | KMT2A (0.50) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL9331092 | 0.78 | KMT2A (0.50) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL6253627 | 0.78 | KMT2A (0.50) | KMT2AMEN1F2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL27600561 | 0.76 | KMT2A (0.49) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL22532073 | 0.75 | F2 (0.49) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL11042682 | 0.74 | MAPT (0.51) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL187697 | 0.74 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1TYMSTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460404-A | HERBICIDES PLANT GROWTH REGULATORS | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0030141-B1 | HERBICIDAL UREAS AND ISOUREAS, PREPARATION, COMPOSITIONS AND USE THEREOF, INTERMEDIATES THEREFOR AND PREPARATION OF SAID INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4452627-A | HERBICIDE, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4370479-A | PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-25 | — | — | US | disclosed |
| EP-0030141-A2 | Herbicidal ureas and isoureas, preparation, compositions and use thereof, intermediates therefor and preparation of said intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-06-10 | — | — | EP | disclosed |