Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042885 | 0.84 | KMT2A (0.45) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL5654867 | 0.80 | VCAM1 (0.40) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL6677573 | 0.79 | GAA (0.36) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL11007951 | 0.79 | ALDH1A1 (0.50) | KMT2AMEN1CA1CA2ALDH1A1 | |
| SCHEMBL31259921 | 0.76 | NFE2L2 (0.38) | KMT2AALDH1A1TDP1 | |
| SCHEMBL5268908 | 0.76 | NFE2L2 (0.38) | KMT2AALDH1A1TDP1 | |
| SCHEMBL10864649 | 0.75 | LMNA (0.43) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL30446303 | 0.75 | KMT2A (1.00) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL11566827 | 0.75 | KMT2A (1.00) | F2PRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL2039879 | 0.75 | KMT2A (1.00) | F2PRSS1PRSS2PRSS3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379769-A | Process for preparing arylsulfonyl isocyanates by phosgenation of arylsulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-04-12 | — | — | US | claimed |
| CN-102540713-A | Resin composition for laser engraving, relief printing plate precursor for laser engraving and process for producing same, and process for making relief printing plate | FUJIFILM CORP | 2012-07-04 | — | — | CN | disclosed |
| US-7030274-B2 | Process for the production of carbodiimide modified organic isocyanates | BAYER MATERIALSCIENCE LLC (US) | 2006-04-18 | — | — | US | disclosed |
| US-20050282993-A1 | Process for the production of carbodiimide modified organic isocyanates | COVESTRO LLC | 2005-12-22 | — | — | US | disclosed |
| EP-1607425-A1 | Process for the production of carboiimide modified organic isocyanates | Bayer MaterialScience LLC (US) | 2005-12-21 | — | — | EP | disclosed |
| US-6413911-B1 | REACTING A SULFONYL ISOCYANATE WITH A 2-AMINO-1,3,5-TRIAZINE OR 2-AMINOPYRIMIDINE, OR REACTING A SULFONAMIDE WITH A PHENYL CARBAMATE OR ISOCYANATE OF -1,3,5-TRIAZINE OR PYRIDINE | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-02 | — | — | US | disclosed |
| US-20020049321-A1 | Herbicidal sulfonylureas, their preparation and use | MAYER HORST (DE) | 2002-04-25 | — | — | US | disclosed |
| US-6362247-B1 | DEACTIVATION PHOSPHOLENE CATALYSTS | ROHM AND HAAS COMPANY | 2002-03-26 | — | — | US | disclosed |
| US-6320046-B1 | A 2-AMINO-1,3,5-TRIAZINE AS CHEMICAL INTERMEDIATE; HIGH SELECTIVITY IN SENSITIVE CROPS | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-20 | — | — | US | disclosed |
| EP-0628034-B1 | N- (1,3,5-TRIAZINE-2-YL)AMINOCARBONYL]BENZENE SULPHONAMIDE HERBICIDES | BASF AG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-4379769-A | Process for preparing arylsulfonyl isocyanates by phosgenation of arylsulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-04-12 | — | — | US | disclosed |
| EP-0073562-A2 | Herbicidal triazole ureas | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-03-09 | — | — | EP | disclosed |
| US-4339266-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4339267-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4257802-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| EP-0021641-A1 | Process for preparing arylsulfonyl isocyanates by phosgenation of arylsulfonamides, and the products of the process and their use | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-01-07 | — | — | EP | disclosed |
| EP-0015683-A1 | Herbicidal sulfonamides, and preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-09-17 | — | — | EP | disclosed |
| US-4214890-A | PRE- AND POST-EMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-29 | — | — | US | disclosed |
| EP-0009419-A1 | Agricultural sulfonamides, and preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-04-02 | — | — | EP | disclosed |
| EP-0001514-A2 | Herbicidal sulfonamides, and preparation and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049321-A1 | Herbicidal sulfonylureas, their preparation and use | SLC5A1, DDT, SLC5A2 | F2 3887/4885PRSS1 3421/4885PRSS2 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.