Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | SMARCA2 | P51531 | 3/20 | 0.55 |
| ▸ | SMARCA4 | P51532 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619959 | 0.83 | SMARCA2 (0.55) | KDRSMARCA2SMARCA4KMT2AMEN1 | |
| SCHEMBL119685 | 0.83 | SMARCA2 (0.79) | KDRSMARCA2SMARCA4KMT2AMEN1 | |
| SCHEMBL13407710 | 0.81 | IDO1 (0.57) | SMARCA2SMARCA4KDM4EGAA | |
| SCHEMBL4523419 | 0.77 | SMARCA2 (0.56) | ALDH1A1HSD17B10TAS2R38SMARCA2SMARCA4 | |
| Phenylurea SCHEMBL8780484 | 0.77 | SMARCA2 (0.68) | KDRSMARCA2SMARCA4KMT2AMEN1 | |
| SCHEMBL1415496 | 0.77 | ALDH1A1 (0.52) | ALDH1A1CYP3A4HSD17B10SMARCA2SMARCA4 | |
| SCHEMBL11371907 | 0.76 | CYP1A2 (0.55) | ALDH1A1CYP3A4HSD17B10TAS2R38KDR | |
| SCHEMBL16566469 | 0.76 | ALDH1A1 (0.74) | ALDH1A1CYP3A4HSD17B10TAS2R38KMT2A | |
| SCHEMBL28821933 | 0.75 | JAK2 (0.63) | SMARCA2SMARCA4KMT2AMEN1NPC1 | |
| SCHEMBL132620 | 0.75 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10TAS2R38KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31550-E | N-(2-Chloro-4-pyridyl) ureas | Shudo, Koichi (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4193788-A | N-(2-Chloro-4-pyridyl)ureas | ISOGAI YO (JP) | 1980-03-18 | — | — | US | disclosed |