Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.74 |
| ▸ | CA9 | Q16790 | 2/20 | 0.66 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132620 | 0.86 | ALDH1A1 (1.00) | ALDH1A1CYP3A4HSD17B10TAS2R38GAA | |
| SCHEMBL8956322 | 0.84 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HSD17B10TAS2R38GAA | |
| SCHEMBL9470190 | 0.84 | ALDH1A1 (0.94) | ALDH1A1CYP3A4HSD17B10TAS2R38GAA | |
| SCHEMBL11186307 | 0.82 | PKM (0.69) | ALDH1A1CYP3A4HSD17B10TAS2R38KMT2A | |
| SCHEMBL11095557 | 0.80 | ALDH1A1 (0.63) | ALDH1A1CYP3A4HSD17B10TAS2R38GAA | |
| SCHEMBL6297654 | 0.80 | CA9 (1.00) | ALDH1A1CA9GAAKMT2AMEN1 | |
| Thiourea SCHEMBL21055683 | 0.79 | ALDH1A1 (0.85) | ALDH1A1CYP3A4HSD17B10TAS2R38GAA | |
| SCHEMBL9297614 | 0.79 | MDM2 (0.56) | ALDH1A1CA9TAAR1EPHX1GAA | |
| SCHEMBL6815965 | 0.79 | MAPT (0.66) | ALDH1A1CYP3A4HSD17B10TAS2R38CA9 | |
| SCHEMBL29924720 | 0.79 | SMN1; SMN2 (0.62) | ALDH1A1CYP3A4HSD17B10TAS2R38CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | RAHMAN ATTA-UR (PK) | 2015-03-19 | — | — | US | disclosed |
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | RAHMAN ATTA-UR (PK) | 2015-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150080580-A1 | THIOUREA DERIVATIVES AS a-CHYMOTRYPSIN INHIBITORS | SERPINB1, CTRL, RNASE1 | ALDH1A1 1629/4885CYP3A4 154/4885HSD17B10 3431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.