Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045169 | 0.83 | KMT2A (0.53) | ALDH1A1SIGMAR1MEN1KMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL11043877 | 0.83 | MAPK14 (0.54) | KDM4EALDH1A1LMNASIGMAR1MEN1 | |
| SCHEMBL11062358 | 0.78 | SIGMAR1 (0.58) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL5280593 | 0.78 | HRH4 (0.58) | KDM4EALDH1A1LMNASIGMAR1MEN1 | |
| Hydrochloric Acid SCHEMBL11039487 | 0.77 | SIGMAR1 (0.57) | KDM4EALDH1A1SIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11048433 | 0.77 | PARP1 (0.52) | ALDH1A1MEN1KMT2A | |
| SCHEMBL9853919 | 0.76 | SIGMAR1 (0.64) | KDM4EALDH1A1LMNASIGMAR1MEN1 | |
| SCHEMBL11041128 | 0.75 | RXFP1 (0.51) | SIGMAR1HRH4DRD4 | |
| SCHEMBL13149475 | 0.74 | NPC1 (0.73) | KDM4EALDH1A1LMNASIGMAR1MEN1 | |
| SCHEMBL15961276 | 0.74 | SIGMAR1 (0.91) | KDM4EALDH1A1SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |