Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11039487 | 0.99 | SIGMAR1 (0.57) | SIGMAR1MEN1KMT2AHRH4MAPK14 | |
| SCHEMBL11045581 | 0.87 | MAPK14 (0.72) | SIGMAR1MEN1KMT2AMAPK14PDE3B | |
| Hydrochloric Acid SCHEMBL11042987 | 0.85 | MAPK14 (0.69) | SIGMAR1MEN1KMT2AMAPK14PDE3B | |
| SCHEMBL13149475 | 0.84 | NPC1 (0.73) | SIGMAR1MEN1KMT2ANPC1KCNH2 | |
| SCHEMBL11071009 | 0.82 | DRD3 (0.66) | SIGMAR1MEN1KMT2APDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL11041259 | 0.82 | DRD3 (0.65) | SIGMAR1MEN1KMT2APDE3BPDE3A | |
| SCHEMBL604630 | 0.79 | HRH4 (0.87) | SIGMAR1HRH4DRD2 | |
| SCHEMBL6093708 | 0.78 | MAPK14 (0.79) | SIGMAR1MEN1KMT2AHRH4MAPK14 | |
| SCHEMBL11043383 | 0.78 | KDM4E (0.54) | SIGMAR1MEN1KMT2AHRH4KCNH2 | |
| Hydrochloric Acid SCHEMBL11043877 | 0.78 | MAPK14 (0.54) | SIGMAR1MEN1KMT2AHRH4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | claimed |