Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15961276 | 0.82 | SIGMAR1 (0.91) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL27564901 | 0.80 | SIGMAR1 (0.73) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7130439 | 0.78 | LMNA (0.72) | KDM4EALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL25237094 | 0.78 | SIGMAR1 (1.00) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7287285 | 0.78 | SIGMAR1 (0.74) | SIGMAR1FAAH | |
| Hydrochloric Acid SCHEMBL11788606 | 0.78 | ALDH1A1 (0.74) | SIGMAR1KDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL11788348 | 0.77 | ALDH1A1 (0.68) | SIGMAR1KDM4EALDH1A1LMNAFAAH | |
| SCHEMBL30671731 | 0.77 | SIGMAR1 (0.97) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17695832 | 0.76 | SIGMAR1 (0.76) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11788201 | 0.76 | ALDH1A1 (0.67) | SIGMAR1KDM4EALDH1A1LMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |