Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 5/20 | 0.32 |
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10883942 | 0.88 | LTA4H (0.38) | LTA4HCA4KCNA3 | |
| SCHEMBL6046974 | 0.77 | LTA4H (0.43) | ALDH1A1RECQLLTA4HCA4L3MBTL1 | |
| SCHEMBL6047053 | 0.69 | LTA4H (0.39) | ALDH1A1RECQLLTA4HCA4KCNA3 | |
| SCHEMBL16241824 | 0.68 | NPSR1 (0.38) | ALDH1A1RECQLLTA4HLMNACA4 | |
| Diphenylether SCHEMBL8691831 | 0.68 | LTA4H (0.67) | ALDH1A1RECQLLTA4HRIPK1LMNA | |
| SCHEMBL6047041 | 0.68 | HTR7 (0.33) | ALDH1A1LTA4HRIPK1LMNA | |
| SCHEMBL9816269 | 0.67 | LTA4H (0.40) | LTA4HRIPK1LMNACA4L3MBTL1 | |
| Alcohol SCHEMBL28150987 | 0.67 | PPARA (0.43) | ALDH1A1RECQLPPARGPPARANPSR1 | |
| Diphenylether SCHEMBL3248800 | 0.66 | LTA4H (0.63) | ALDH1A1RECQLLTA4HRIPK1LMNA | |
| Anisole SCHEMBL3601309 | 0.66 | CA4 (0.74) | ALDH1A1RECQLLTA4HCA4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111789-A1 | Bis(beta-pentabromophenoxyethyl) succinate, a flame retardant for ABS | BORG-WARNER CHEMICALS INC. (US) | 1984-06-27 | — | — | EP | disclosed |