SCHEMBL11043528

SCHEMBL11043528

Cc1ccc(C(C)C)c(Oc2cc(C)ccc2C(C)C)c1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
TRPA1 O75762 1/20 0.54
CHRM1 P11229 1/20 0.54
SLC6A2 P23975 1/20 0.54
ADRA1A P35348 1/20 0.54
HTR2B P41595 1/20 0.54
ALDH1A1 P00352 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
TSHR P16473 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
KDM4E B2RXH2 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
MAOA P21397 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29640497 1.00 LMNA (0.54) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL29087264 0.90 HTR2A (0.51) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL29527491 0.86 LMNA (0.54) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL9463062 0.86 LMNA (0.54) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL17629451 0.84 ACHE (0.58) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL30033430 0.84 ACHE (0.58) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL196752 0.84 ACHE (0.58) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL29583808 0.84 ALDH1A1 (0.53) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL11185126 0.83 ACHE (0.47) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL31545975 0.83 LMNA (0.56) LMNATRPA1CHRM1SLC6A2ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105732703-A HIGHLY SELECTIVE PROCESS FOR PRODUCING ORGANODIPHOSPHITES 因温斯特技术公司 2016-07-06 CN disclosed
CN-102405226-A Highly selective process for the preparation of organodiphosphites INVISTA TECH SARL 2012-04-04 CN disclosed
CN-102405225-A Highly selective process for the preparation of organodiphosphites INVISTA TECH SARL 2012-04-04 CN disclosed
US-4463112-A STABILIZED COMPOSITIONS PHOENIX CHEMICAL CORPORATION, A CORP. OF DE. 1984-07-31 US disclosed
US-3966779-A SYMPATHOLYTIC WARNER-LAMBERT COMPANY (US) 1976-06-29 US disclosed