Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | DNMT3B | Q9UBC3 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28594943 | 0.75 | ALDH1A1 (0.54) | CA2DNMT3BKMT2AMEN1MAPT | |
| SCHEMBL11040785 | 0.75 | CA2 (0.49) | CA2KMT2AMEN1MAPTKDM4E | |
| SCHEMBL11040615 | 0.75 | CA2 (0.58) | CA2KMT2AKDM4ETP53ALDH1A1 | |
| SCHEMBL11041002 | 0.75 | CA2 (0.58) | CA2DNMT3BKMT2AMEN1KDM4E | |
| SCHEMBL11056275 | 0.75 | CA2 (0.58) | CA2KMT2AMEN1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL11039231 | 0.73 | CA2 (0.56) | CA2MAPTKDM4EALDH1A1CACNA1F | |
| SCHEMBL11039068 | 0.72 | CA2 (0.54) | CA2TDP2KDM4CMAPTKDM4E | |
| SCHEMBL9096555 | 0.72 | CA2 (0.46) | CA2KMT2AMAPTKDM4EGAA | |
| SCHEMBL11451918 | 0.71 | GPR35 (0.50) | DNMT3BKMT2AMEN1MAPTKDM4E | |
| SCHEMBL11451916 | 0.71 | GPR35 (0.50) | DNMT3BKMT2AMEN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |