Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.83 |
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 2/20 | 0.83 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.83 |
| ▸ | HTT | P42858 | 2/20 | 0.83 |
| ▸ | PKM | P14618 | 1/20 | 0.83 |
| ▸ | HPGD | P15428 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.82 |
| ▸ | RAB9A | P51151 | 1/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.82 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.68 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.63 |
| ▸ | MMP3 | P08254 | 1/20 | 0.63 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13297325 | 1.00 | ESR1 (0.83) | ESR1LMNAMAPTESR2HTT | |
| SCHEMBL3470674 | 1.00 | ESR1 (0.83) | ESR1LMNAMAPTESR2HTT | |
| SCHEMBL6420024 | 1.00 | ESR1 (0.83) | ESR1LMNAMAPTESR2HTT | |
| SCHEMBL4671519 | 1.00 | ESR1 (0.83) | ESR1LMNAMAPTESR2HTT | |
| SCHEMBL10535107 | 1.00 | ESR1 (0.83) | ESR1LMNAMAPTESR2HTT | |
| SCHEMBL699850 | 0.91 | LMNA (1.00) | ESR1LMNAMAPTESR2HTT | |
| SCHEMBL18423 | 0.91 | LMNA (1.00) | ESR1LMNAMAPTESR2HTT | |
| SCHEMBL2214895 | 0.91 | RAB9A (1.00) | ESR1LMNAMAPTESR2HTT | |
| SCHEMBL7929339 | 0.91 | MAPT (0.91) | ESR1LMNAMAPTESR2HTT | |
| SCHEMBL10871402 | 0.89 | LMNA (0.67) | ESR1LMNAMAPTESR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057503-B1 | PRODUCTION OF HYDROXY ARYLOPHENONES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-20 | — | — | EP | disclosed |
| US-4453010-A | Production of hydroxy arylophenones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-05 | — | — | US | disclosed |
| EP-0075390-A1 | Production of arylophenones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-03-30 | — | — | EP | disclosed |
| EP-0057503-A1 | Production of hydroxy arylophenones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-08-11 | — | — | EP | disclosed |