Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222922 | 0.83 | ALDH1A1 (0.44) | ACE2ALDH1A1ATMCA2MAPK1 | |
| SCHEMBL8930066 | 0.82 | GABRR1 (0.46) | ACE2CYP1A2GABRR1 | |
| SCHEMBL446836 | 0.82 | ACE2 (0.46) | ACE2ALDH1A1TSHRCYP1A2 | |
| SCHEMBL16299711 | 0.82 | ACE2 (0.46) | ACE2ALDH1A1TSHRCYP1A2 | |
| Bicarbonate SCHEMBL1538407 | 0.78 | ALDH1A1 (0.52) | ALDH1A1ATMHCAR2GPR84FFAR1 | |
| SCHEMBL11844397 | 0.76 | USP2 (0.48) | ACE2CYP1A2 | |
| Acetic Acid SCHEMBL2136672 | 0.75 | ALDH1A1 (0.56) | ALDH1A1ATMHCAR2GPR84FFAR1 | |
| SCHEMBL10611374 | 0.75 | CA2 (0.65) | ALDH1A1ATMCA2MAPK1HCAR2 | |
| SCHEMBL27804893 | 0.75 | ACE2 (0.47) | ACE2ALDH1A1HCAR2GPR84FFAR1 | |
| SCHEMBL298769 | 0.74 | ALDH1A1 (0.38) | ALDH1A1ATMTSHRTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435473-A | POLYMER REINFORCEMENT | PPG INDUSTRIES, INC. (US) | 1984-03-06 | — | — | US | disclosed |