SCHEMBL1104376

SCHEMBL1104376

CCN1C(=O)/C(=C\c2ccc(N(c3ccc(OC)cc3)c3ccc(OC)cc3)cc2)OC1=NC1CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
LMNA P02545 1/20 0.44
HPGD P15428 1/20 0.43
MAPT P10636 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
ACHE P22303 1/20 0.38
MAOB P27338 4/20 0.38
HSD17B3 P37058 1/20 0.37
MGAM O43451 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
KMT2A Q03164 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MEN1 O00255 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12514694 1.00 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL13964815 0.96 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL12442002 0.96 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL13360053 0.95 HSD17B3 (0.44) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL1104387 0.89 KMT2A (0.35) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL12442004 0.89 KMT2A (0.35) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL12442001 0.89 MEN1 (0.39) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL1104374 0.89 MEN1 (0.39) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL12514695 0.86 SMN1; SMN2 (0.44) ALDH1A1SMN1; SMN2LMNAHPGDMAPT
SCHEMBL1104389 0.86 SMN1; SMN2 (0.44) ALDH1A1SMN1; SMN2LMNAHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2037323-B1 Photosensitive compositions FUJIFILM CORP (JP) 2014-12-10 EP disclosed
US-8785087-B2 Pigment-dispersed composition, curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2014-07-22 US disclosed
US-8785087-B2 Pigment-dispersed composition, curable composition, color filter and production method thereof FUJIFILM CORPORATION (JP) 2014-07-22 US disclosed
US-8778575-B2 Curable composition, color filter using the same and manufacturing method therefor, and solid image pickup element FUJIFILM CORPORATION (JP) 2014-07-15 US disclosed
US-8778575-B2 Curable composition, color filter using the same and manufacturing method therefor, and solid image pickup element FUJIFILM CORPORATION (JP) 2014-07-15 US disclosed
US-8728686-B2 Photosensitive compositions, curable compositions, novel compounds, photopolymerizable compositions, color filters, and planographic printing plate precursors FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-8728686-B2 Photosensitive compositions, curable compositions, novel compounds, photopolymerizable compositions, color filters, and planographic printing plate precursors FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-8551676-B2 Pigment-dispersed composition, curable composition, and color filter and production method thereof FUJIFILM CORPORATION (JP) 2013-10-08 US disclosed
US-8551676-B2 Pigment-dispersed composition, curable composition, and color filter and production method thereof FUJIFILM CORPORATION (JP) 2013-10-08 US disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-20090023085-A1 Photosensitive Compositions, Curable Compositions, Novel Compounds, Photopolymerizable Compositions, Color Filters, and Planographic Printing Plate Precursors FUJIFILM CORPORATION (JP) 2009-01-22 US disclosed
US-20080268372-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-20080268372-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-20080261153-A1 PLATE MAKING METHOD OF LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2008-10-23 US disclosed
US-20080241713-A1 COLORED PHOTOCURABLE COMPOSITION FOR SOLID STATE IMAGE PICK-UP DEVICE, COLOR FILTER AND METHOD FOR PRODUCTION THEREOF, AND SOLID STATE IMAGE PICK-UP DEVICE FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080241713-A1 COLORED PHOTOCURABLE COMPOSITION FOR SOLID STATE IMAGE PICK-UP DEVICE, COLOR FILTER AND METHOD FOR PRODUCTION THEREOF, AND SOLID STATE IMAGE PICK-UP DEVICE FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080171272-A1 CURABLE COMPOSITION, COLOR FILTER USING THE SAME AND MANUFACTUIRNG METHOD THEREFOR, AND SOLID IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2008-07-17 US disclosed
US-20080171272-A1 CURABLE COMPOSITION, COLOR FILTER USING THE SAME AND MANUFACTUIRNG METHOD THEREFOR, AND SOLID IMAGE PICKUP ELEMENT FUJIFILM CORPORATION (JP) 2008-07-17 US disclosed
US-20080076043-A1 CURABLE COMPOSITION, COLOR FILTER AND MANUFACTURING METHOD THEREOF FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-20080076043-A1 CURABLE COMPOSITION, COLOR FILTER AND MANUFACTURING METHOD THEREOF FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023085-A1 Photosensitive Compositions, Curable Compositions, Novel Compounds, Photopolymerizable Compositions, Color Filters, and Planographic Printing Plate Precursors RB1, MC1R, TYR ALDH1A1 512/4885SMN1; SMN2 3564/4885LMNA 3571/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.