SCHEMBL12442001

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1104374	1.00	MEN1 (0.39)	MEN1KMT2AALDH1A1ALOX15FAAH
	SCHEMBL12442004	0.92	KMT2A (0.35)	MEN1KMT2AALDH1A1FAAHHPGD
	SCHEMBL1104387	0.92	KMT2A (0.35)	MEN1KMT2AALDH1A1FAAHHPGD
	SCHEMBL12441974	0.89	ALDH1A1 (0.39)	MEN1KMT2AALDH1A1ALOX15FAAH
	SCHEMBL12441988	0.89	ALDH1A1 (0.39)	MEN1KMT2AALDH1A1ALOX15FAAH
	SCHEMBL1104379	0.89	ALDH1A1 (0.39)	MEN1KMT2AALDH1A1ALOX15FAAH
	SCHEMBL1104353	0.89	ALDH1A1 (0.39)	MEN1KMT2AALDH1A1ALOX15FAAH
	SCHEMBL21118762	0.89	FAAH (0.37)	MEN1KMT2AALDH1A1ALOX15FAAH
	SCHEMBL1104376	0.89	ALDH1A1 (0.44)	MEN1KMT2AALDH1A1HPGDSMN1; SMN2
	SCHEMBL12514694	0.89	ALDH1A1 (0.44)	MEN1KMT2AALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.