SCHEMBL12442002

SCHEMBL12442002

CCN1C(=O)/C(=C\c2ccc(N(c3ccc(C)cc3)c3ccc(OC)cc3)cc2)O/C1=N/C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.42
HPGD P15428 1/20 0.42
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
ALOX5 P09917 3/20 0.38
MAPT P10636 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACHE P22303 1/20 0.36
MAOB P27338 3/20 0.36
HSD17B3 P37058 1/20 0.35
PPARG P37231 1/20 0.34
MGAM O43451 1/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13964815 1.00 SMN1; SMN2 (0.42) SMN1; SMN2HPGDALDH1A1LMNAALOX5
SCHEMBL12514694 0.96 ALDH1A1 (0.44) SMN1; SMN2HPGDALDH1A1LMNAMAPT
SCHEMBL1104376 0.96 ALDH1A1 (0.44) SMN1; SMN2HPGDALDH1A1LMNAMAPT
SCHEMBL12442004 0.94 KMT2A (0.35) SMN1; SMN2HPGDALDH1A1LMNAMAPT
SCHEMBL1104387 0.94 KMT2A (0.35) SMN1; SMN2HPGDALDH1A1LMNAMAPT
SCHEMBL13360053 0.92 HSD17B3 (0.44) SMN1; SMN2HPGDALDH1A1LMNAMAPT
SCHEMBL12442000 0.88 KMT2A (0.38) SMN1; SMN2HPGDALDH1A1LMNAMAPT
SCHEMBL13964810 0.88 KMT2A (0.38) SMN1; SMN2HPGDALDH1A1LMNAMAPT
SCHEMBL12442005 0.88 SMN1; SMN2 (0.41) SMN1; SMN2HPGDALDH1A1LMNAALOX5
SCHEMBL13964817 0.88 SMN1; SMN2 (0.41) SMN1; SMN2HPGDALDH1A1LMNAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9032876-B2 Lithographic printing plate precursor, lithographic printing plate platemaking method, and polymerizable monomer FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
US-20110174179-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING PLATE PLATEMAKING METHOD, AND POLYMERIZABLE MONOMER FUJIFILM CORPORATION (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110174179-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING PLATE PLATEMAKING METHOD, AND POLYMERIZABLE MONOMER SORT1, ELOVL6, SCD5 SMN1; SMN2 1252/4885HPGD 1651/4885ALDH1A1 2027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.