Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 12/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 11/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.51 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.51 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.51 |
| ▸ | IDH1 | O75874 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042762 | 0.89 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL28101470 | 0.81 | CYP11B1 (0.74) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL15872000 | 0.80 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL11073946 | 0.79 | CYP11B1 (0.67) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL23045637 | 0.79 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL5592268 | 0.76 | IDH1 (0.55) | CYP11B1CYP11B2CYP19A1POLBMAPT | |
| SCHEMBL26130051 | 0.76 | ALDH1A1 (0.62) | CYP11B1CYP11B2CYP19A1CYP2A6CYP2B6 | |
| Oxalic Acid SCHEMBL11084954 | 0.75 | TBXAS1 (0.58) | CYP11B1CYP11B2CYP19A1TBXAS1 | |
| SCHEMBL14035867 | 0.74 | CYP11B1 (0.59) | CYP11B1CYP11B2CYP19A1TBXAS1CYP2A6 | |
| SCHEMBL23045676 | 0.74 | CYP11B1 (0.73) | CYP11B1CYP11B2CYP19A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0104572-A1 | Benzyl ethers of phenol Mannich bases, process for their production, their use and pharmaceutical preparations based on these compounds, intermediates and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-04-04 | — | — | EP | disclosed |