Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610709 | 0.85 | CYP11B1 (0.54) | IDH1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL4290436 | 0.79 | CYP11B1 (0.62) | CYP11B1CYP11B2KDM4EHSD17B10CYP19A1 | |
| SCHEMBL30168127 | 0.79 | CYP11B1 (0.62) | CYP11B1CYP11B2BRD4KDM4EHSD17B10 | |
| SCHEMBL11043846 | 0.76 | CYP11B1 (0.67) | IDH1CYP11B1CYP11B2CYP19A1POLB | |
| SCHEMBL5592277 | 0.76 | CYP11B1 (0.57) | IDH1CYP11B1CYP11B2BRD4KDM4E | |
| SCHEMBL23045637 | 0.73 | CYP11B1 (0.64) | IDH1CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL5610866 | 0.72 | ALDH1A1 (0.54) | CYP11B1CYP11B2MEN1KMT2ACYP19A1 | |
| SCHEMBL5610972 | 0.72 | CYP11B1 (0.60) | CYP11B1CYP11B2BRD4CYP19A1POLB | |
| SCHEMBL5161458 | 0.71 | PRKCI (0.46) | MEN1KMT2AKDM4EHSD17B10CYP19A1 | |
| SCHEMBL13105206 | 0.71 | CYP11B1 (0.58) | IDH1CYP11B1CYP11B2CYP19A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079800-A1 | IMIDAZOLYLMETHYL-SUBSTITUTED DEVELOPERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-07-19 | — | — | WO | claimed |
| WO-2007079800-A1 | IMIDAZOLYLMETHYL-SUBSTITUTED DEVELOPERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007079800-A1 | IMIDAZOLYLMETHYL-SUBSTITUTED DEVELOPERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-07-19 | — | — | WO | disclosed |