Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.57 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | THRA | P10827 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1404028 | 0.91 | RARB (0.67) | RARBPLK1THRATHRBALDH1A1 | |
| Acetic Acid SCHEMBL27813854 | 0.85 | ALDH1A1 (0.61) | RARBPLK1HTR7THRATHRB | |
| SCHEMBL617127 | 0.85 | RARB (0.68) | RARBTHRATHRBALDH1A1 | |
| SCHEMBL1054597 | 0.84 | FFAR1 (0.59) | ALDH1A1LMNAGAAHPGDHSD17B10 | |
| SCHEMBL7485086 | 0.84 | ESR1 (0.63) | RARBPLK1THRATHRBALDH1A1 | |
| SCHEMBL4603474 | 0.84 | TRPV1 (0.64) | RARBPLK1THRATHRBALDH1A1 | |
| SCHEMBL15871050 | 0.84 | FFAR1 (0.53) | RARBPLK1HTR7THRATHRB | |
| SCHEMBL15453509 | 0.83 | THRA (0.69) | RARBTHRATHRBALDH1A1TDP1 | |
| SCHEMBL7651082 | 0.83 | THRA (0.69) | RARBTHRATHRBALDH1A1TDP1 | |
| SCHEMBL28937868 | 0.83 | THRA (0.69) | RARBTHRATHRBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453009-A | HALOGEN-FLUORINE EXCHANGE BETWEEN CORRESPONDING 4-HALOGENO- OR 4,4-DIHALOGENOBENZOPHENONE AND ALKALI FLUORIDE | MITSUI TOATSU CHEMICALS, INC. (JP) | 1984-06-05 | — | — | US | disclosed |
| US-4145444-A | 4-BUTYL-BENZOPHENONE | KAKEN CHEMICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4124726-A | 2-FLUORO-4'-ALKYLBENZOPHENONE | KAKEN CHEMICAL CO., LTD. (JP) | 1978-11-07 | — | — | US | disclosed |