Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435075 | 0.79 | NPC1 (0.61) | KDM4EALDH1A1CYP1A2HPGDKMT2A | |
| SCHEMBL3962704 | 0.78 | KDM4E (0.48) | KDM4EALDH1A1CYP1A2HPGDKMT2A | |
| SCHEMBL1977970 | 0.78 | BACE1 (0.56) | KDM4EALDH1A1CYP1A2HPGDKMT2A | |
| SCHEMBL28453909 | 0.78 | MEN1 (0.44) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL3987179 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL3987798 | 0.77 | MAPT (0.43) | KDM4EALDH1A1CYP1A2HPGDKMT2A | |
| SCHEMBL8381209 | 0.77 | KMT2A (0.51) | KDM4EALDH1A1CYP1A2KMT2AMAPT | |
| SCHEMBL3991199 | 0.77 | PTPN1 (0.41) | KDM4EALDH1A1HPGDKMT2AMAPT | |
| SCHEMBL4159853 | 0.75 | KMT2A (0.49) | KDM4EALDH1A1CYP1A2HPGDKMT2A | |
| SCHEMBL1104364 | 0.75 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108586354-B | Benzimidazole derivative and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-09-22 | — | — | CN | disclosed |
| US-20120295204-A1 | PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR | FUJIFILM CORPORATION (JP) | 2012-11-22 | — | — | US | disclosed |
| US-8257913-B2 | Processing method of lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-09-04 | — | — | US | disclosed |
| US-8168370-B2 | Photosensitive composition which included photopolymerization initiator; graft polymer binder | FUJIFILM CORPORATION (JP) | 2012-05-01 | — | — | US | disclosed |
| US-8151705-B2 | Method of preparing lithographic printing plate | FUJIFILM CORPORATION (JP) | 2012-04-10 | — | — | US | disclosed |
| US-7985535-B2 | Image-forming method and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2011-07-26 | — | — | US | disclosed |
| US-20110091814-A1 | PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| US-7923197-B2 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2011-04-12 | — | — | US | disclosed |
| US-20110017084-A1 | IMMERSION TYPE AUTOMATIC DEVELOPING APPARATUS FOR LITHOGRAPHIC PRINTING PLATE AND AUTOMATIC DEVELOPING METHOD | FUJIFILM CORPORATION (JP) | 2011-01-27 | — | — | US | disclosed |
| US-20110020751-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRODUCTION PROCESS OF LITHOGRAPHIC PRINTING PLATE USING THE PRECURSOR | FUJIFILM CORPORATION (JP) | 2011-01-27 | — | — | US | disclosed |
| US-20070207411-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2007-09-06 | — | — | US | disclosed |
| US-20070184387-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070128550-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2007-06-07 | — | — | US | disclosed |
| US-20070020563-A1 | Method for preparation of lithographic printing plate and lithographic printing plate precursor | FUJI PHOTO FILM CO., LTD. | 2007-01-25 | — | — | US | disclosed |
| US-7148226-B2 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | AGOURON PHARMACEUTICALS, INC. (US) | 2006-12-12 | — | — | US | disclosed |
| US-20060189681-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | AGOURON PHARMACEUTICALS, INC. | 2006-08-24 | — | — | US | disclosed |
| EP-1597246-A2 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2005-11-23 | — | — | EP | disclosed |
| US-20050176701-A1 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | AGOURON PHARMACEUTICALS, INC. | 2005-08-11 | — | — | US | disclosed |
| WO-2004074270-A2 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2004-09-02 | — | — | WO | disclosed |
| US-4520196-A | α-Mercaptophenylacetic acid derivatives of imidazole-containing compounds and analogues thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1985-05-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189681-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | RNASE1, RNASEH1, NSUN3 | KDM4E 1534/4885ALDH1A1 322/4885CYP1A2 164/4885 |
| US-20050176701-A1 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | RNASE1, RNASEH1, NSUN3 | KDM4E 1534/4885ALDH1A1 322/4885CYP1A2 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.