SCHEMBL2202012

SCHEMBL2202012

CCn1c(S)nc2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.62
CYP1A2 P05177 2/20 0.62
CYP2D6 P10635 1/20 0.62
KMT2A Q03164 3/20 0.57
PKM P14618 2/20 0.57
MEN1 O00255 2/20 0.57
KDM4E B2RXH2 7/20 0.56
ALDH1A1 P00352 7/20 0.56
HPGD P15428 6/20 0.56
LMNA P02545 2/20 0.56
MAPK1 P28482 2/20 0.56
HSD17B10 Q99714 2/20 0.56
POLB P06746 3/20 0.54
MAPT P10636 4/20 0.53
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
GLA P06280 1/20 0.53
GAA P10253 1/20 0.53
NFKB1 P19838 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3140332 0.85 POLB (0.65) HTTCYP1A2CYP2D6KMT2AMEN1
SCHEMBL14557079 0.84 CXCR4 (0.52) HTTCYP1A2CYP2D6KMT2APKM
SCHEMBL3840545 0.82 TLR8 (0.67) HTTKMT2AMEN1KDM4EALDH1A1
SCHEMBL3137088 0.81 TLR8 (0.68) HTTCYP1A2CYP2D6ALDH1A1POLB
SCHEMBL11350545 0.81 CYP1A2 (0.44) HTTCYP1A2CYP2D6KMT2APKM
SCHEMBL14112988 0.81 MEN1 (0.49) HTTCYP1A2CYP2D6KMT2APKM
SCHEMBL1104424 0.80 KDM4E (0.62) HTTCYP1A2CYP2D6KMT2AMEN1
SCHEMBL12565557 0.80 LMNA (0.56) HTTCYP1A2CYP2D6KMT2AMEN1
SCHEMBL230641 0.80 ALDH1A1 (0.70) HTTCYP1A2CYP2D6KMT2APKM
SCHEMBL3136462 0.80 TLR8 (0.68) HTTCYP1A2CYP2D6ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110845910-A OLED ink for ink-jet printing and preparation method thereof 成都新柯力化工科技有限公司 2020-02-28 CN claimed
CN-108101935-A Silane of one kind structure containing benzimidazole and preparation method thereof 烟台大学 2018-06-01 CN claimed
US-5738969-A WATER INSOLUBLE COMPOUND HAVING MERCAPTO OR THIONE GROUP, AND SULFONATED STYRENE-CONTAINING POLYMER MITSUBISHI PAPER MILLS LIMITED (JP) 1998-04-14 US claimed
US-6423486-B1 None US disclosed
US-20250051320-A1 CRBN LIGANDS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-02-13 US disclosed
US-11932635-B2 CRBN ligands and uses thereof KYMERA THERAPEUTICS, INC. (US) 2024-03-19 US disclosed
CN-116550475-A Sphalerite collecting agent and preparation method and application thereof 广西大学 2023-08-08 CN disclosed
US-20230234950-A1 CRBN LIGANDS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-07-27 US disclosed
US-20230234950-A1 CRBN LIGANDS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-07-27 US disclosed
US-20230234950-A1 CRBN LIGANDS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-07-27 US disclosed
US-11512080-B2 CRBN ligands and uses thereof KYMERA THERAPEUTICS, INC. (US) 2022-11-29 US disclosed
US-5391457-A For silver complex diffusion transfer processing in presence of a triazole, oxadiazole type compound; wear resistance of plates; good ink receptivity; free from waste solution disposal FUJI PHOTO FILM CO., LTD (JP) 1995-02-21 US disclosed
US-5321053-A Curable mixture of vinyl monomer containing acidic group and photoinitiator KURARAY CO., LTD. (JP) 1994-06-14 US disclosed
EP-0559228-A1 Photothermographic elements MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-09-08 EP disclosed
US-5153097-A LIGHT-SENSITIVE MATERIAL FOR LITHOGRAPHIC PRINTING PLATE AND PROCESS FOR MAKING PRINTING PLATE MITSUBISHI PAPER MILLS LIMITED (JP) 1992-10-06 US disclosed
EP-0155812-B1 DENTAL COMPOSITIONS KURARAY CO., LTD. (JP) 1991-09-11 EP disclosed
EP-0087176-B1 METHOD FOR THE PREPARATION OF A PLANOGRAPHIC PRINTING PLATE AGFA-GEVAERT N.V. (BE) 1987-07-01 EP disclosed
US-4563410-A NICKEL SULFIDE; HYDROPHOBIZING SILVER IMAGE AGFA-GEVAERT N.V. (BE) 1986-01-07 US disclosed
US-4353981-A CONTAINING WATER SOLUBLE COMPOUND OF RHODIUM, IRIDIUM OR GOLD; STORAGE STABILITY MITSUBISHI PAPER MILLS, LTD. (JP) 1982-10-12 US disclosed
US-4230792-A COMPLEXING SILVER WITH THIOL OR THIONE MITSUBISHI PAPER MILLS, LTD. (JP) 1980-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230234950-A1 CRBN LIGANDS AND USES THEREOF CRBN, CRKL, ERBB3 HTT 1125/4885CYP1A2 4670/4885CYP2D6 4808/4885
US-11932635-B2 CRBN ligands and uses thereof CRBN, CRKL, ERBB3 HTT 1125/4885CYP1A2 4670/4885CYP2D6 4808/4885
US-20250051320-A1 CRBN LIGANDS AND USES THEREOF CRBN, CRKL, ERBB3 HTT 1125/4885CYP1A2 4670/4885CYP2D6 4808/4885
US-11512080-B2 CRBN ligands and uses thereof CRBN, CRKL, ERBB3 HTT 1125/4885CYP1A2 4670/4885CYP2D6 4808/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.