SCHEMBL1104426

SCHEMBL1104426

Sc1nc2ccccc2n1C1CCCCC1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.58
OGFRL1 Q5TC84 13/20 0.52
OPRM1 P35372 11/20 0.52
OPRK1 P41145 11/20 0.52
OPRD1 P41143 10/20 0.52
PRKACA P17612 3/20 0.52
RPS6KB1 P23443 3/20 0.52
GSK3B P49841 3/20 0.52
ROCK1 Q13464 3/20 0.52
OPRL1 P41146 1/20 0.48
HDAC3 O15379 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC10 Q969S8 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22612126 0.91 CYP11B2 (0.51) TP53OGFRL1OPRM1OPRK1OPRD1
SCHEMBL11791438 0.84 OPRM1 (0.45) TP53OGFRL1OPRM1OPRK1OPRD1
SCHEMBL21311255 0.80 OPRM1 (0.59) TP53OGFRL1OPRM1OPRK1OPRD1
SCHEMBL18250718 0.80 GAA (0.64) TP53OGFRL1OPRM1OPRK1OPRD1
SCHEMBL19851139 0.80 RPS6KA5 (0.55) TP53OGFRL1OPRM1OPRK1OPRD1
SCHEMBL19851079 0.80 PDE4B (0.54) TP53
SCHEMBL3448194 0.78 GAA (0.61) TP53OGFRL1OPRM1OPRK1OPRD1
SCHEMBL13071424 0.78 TP53 (0.60) TP53OGFRL1OPRM1OPRK1OPRD1
SCHEMBL2929873 0.78 RPS6KB1 (0.58) TP53OGFRL1OPRM1OPRK1OPRD1
SCHEMBL1128699 0.78 TP53 (0.56) TP53OGFRL1OPRM1OPRK1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200166846-A1 ON-PRESS DEVELOPMENT TYPE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2020-05-28 US disclosed
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
EP-2503393-B2 Method for preparation of lithographic printing plate FUJIFILM CORP (JP) 2016-07-20 EP disclosed
EP-2088468-B1 Method of preparing lithographic printing plate and lithographic printing plate precursor FUJIFILM CORP (JP) 2016-05-18 EP disclosed
EP-2101218-B1 Method for preparing a lithographic printing plate FUJIFILM CORP (JP) 2015-11-25 EP disclosed
EP-2662729-B1 Method for preparation of lithographic printing plate FUJIFILM CORP (JP) 2014-10-22 EP disclosed
US-8714088-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2014-05-06 US disclosed
EP-2503393-B1 Method for preparation of lithographic printing plate FUJIFILM CORP (JP) 2013-11-13 EP disclosed
EP-2662729-A1 Method for preparation of lithographic printing plate Fujifilm Corporation (JP) 2013-11-13 EP disclosed
US-20120295204-A1 PROCESSING METHOD OF LITHOGRAPHIC PRINTING PLATE PREURSOR FUJIFILM CORPORATION (JP) 2012-11-22 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
EP-1829681-A2 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM Corporation (JP) 2007-09-05 EP disclosed
EP-1640805-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2007-08-22 EP disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed
US-20070020563-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2007-01-25 US disclosed