Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | PNMT | P11086 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.50 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3759207 | 0.94 | IGF1R (0.58) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL3565937 | 0.85 | PNMT (0.61) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL9026676 | 0.79 | IGF1R (0.61) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL1448394 | 0.79 | SIGMAR1 (0.63) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL31497388 | 0.79 | PNMT (0.73) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL4714764 | 0.79 | PNMT (0.73) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL9026682 | 0.79 | IGF1R (0.67) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL11443994 | 0.78 | IGF1R (0.60) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL11332028 | 0.78 | PNMT (0.70) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL10610096 | 0.78 | IGF1R (0.59) | IGF1RALOX15PNMTTAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |