Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.63 |
| ▸ | IGF1R | P08069 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | PNMT | P11086 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | TACR2 | P21452 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066232 | 0.98 | SIGMAR1 (0.61) | SIGMAR1IGF1RALOX15PNMTTAAR1 | |
| SCHEMBL22333700 | 0.98 | SIGMAR1 (0.61) | SIGMAR1IGF1RALOX15PNMTTAAR1 | |
| SCHEMBL9177318 | 0.94 | SIGMAR1 (0.62) | SIGMAR1IGF1RALOX15PNMTTAAR1 | |
| SCHEMBL429772 | 0.85 | PNMT (0.61) | SIGMAR1IGF1RALOX15PNMTTAAR1 | |
| SCHEMBL28114780 | 0.82 | HTR2A (0.48) | SIGMAR1IGF1RALOX15ALDH1A1TP53 | |
| SCHEMBL573937 | 0.82 | IGF1R (0.61) | IGF1RALOX15ALDH1A1TP53ESR1 | |
| SCHEMBL14402440 | 0.82 | HTR2A (0.48) | SIGMAR1ALDH1A1TP53ESR1ADRA2A | |
| SCHEMBL24454689 | 0.81 | HTR2A (0.52) | SIGMAR1ALDH1A1TP53ESR1ADRA2A | |
| SCHEMBL22748316 | 0.81 | ESR1 (0.47) | SIGMAR1ALDH1A1TP53ESR1ADRA2A | |
| SCHEMBL22748319 | 0.81 | ABL1 (0.55) | SIGMAR1ALDH1A1TP53ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292623-A1 | Acylated phthalocyanines | Karlsruher Institut für Technologie (DE) | 2011-03-09 | — | — | EP | claimed |
| US-20170196854-A1 | USE OF ANTHELMINTIC AGENTS AGAINST DIROFILARIA IMMITIS | INTERVET INC. (US) | 2017-07-13 | — | — | US | disclosed |
| US-9346795-B2 | Substituted sulfonamides useful as antiapoptotic Bcl inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-05-24 | — | — | US | disclosed |
| US-20140135318-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-15 | — | — | US | disclosed |
| US-8198433-B2 | Acylated phthalocyanines | KARLSRUHER INSTITUT FUER TECHNOLOGIE (DE) | 2012-06-12 | — | — | US | disclosed |
| EP-2292623-A1 | Acylated phthalocyanines | Karlsruher Institut für Technologie (DE) | 2011-03-09 | — | — | EP | disclosed |
| US-20110054166-A1 | ACYLATED PHTHALOCYANINES | KARLSRUHER INSTITUT FUER TECHNOLOGIE (DE) | 2011-03-03 | — | — | US | disclosed |
| EP-1847533-A1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170196854-A1 | USE OF ANTHELMINTIC AGENTS AGAINST DIROFILARIA IMMITIS | MPO, DHODH, DHX35 | SIGMAR1 4211/4885IGF1R 4789/4885ALOX15 2709/4885 |
| US-20140135318-A1 | SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS | BCL2, BAX, BCL2A1 | SIGMAR1 2792/4885IGF1R 3694/4885ALOX15 3561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.