Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.49 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | CBX7 | O95931 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063813 | 0.94 | TIMP3 (0.52) | ENPP2TIMP3CASP6CTDSP1MEN1 | |
| SCHEMBL11055558 | 0.92 | ENPP2 (0.43) | ENPP2TIMP3CASP6CTDSP1MEN1 | |
| SCHEMBL11049888 | 0.89 | ENPP2 (0.52) | ENPP2TIMP3CASP6CTDSP1MEN1 | |
| SCHEMBL11065963 | 0.87 | TIMP3 (0.48) | ENPP2TIMP3CASP6CTDSP1MEN1 | |
| SCHEMBL11074599 | 0.87 | CASP6 (0.60) | ENPP2TIMP3CASP6CTDSP1PRMT1 | |
| SCHEMBL10541404 | 0.87 | ENPP2 (0.41) | ENPP2TIMP3CASP6CTDSP1MEN1 | |
| SCHEMBL11055518 | 0.86 | TIMP3 (0.48) | ENPP2TIMP3CASP6CTDSP1MEN1 | |
| SCHEMBL11044357 | 0.85 | CASP6 (0.51) | ENPP2TIMP3CASP6CTDSP1MEN1 | |
| SCHEMBL11061185 | 0.85 | TIMP3 (0.39) | ENPP2TIMP3CASP6CTDSP1MEN1 | |
| SCHEMBL11058317 | 0.85 | APEX1 (0.57) | ENPP2TIMP3CASP6CTDSP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |