Methyl Carbamate

Methyl Carbamate

SCHEMBL11044545

CC(=O)N(C)C.COC(N)=O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.43
ALDH1A1 P00352 4/20 0.42
ALOX15 P16050 2/20 0.39
PMP22 Q01453 2/20 0.39
LMNA P02545 1/20 0.39
BLM P54132 1/20 0.39
F2 P00734 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
CRBN Q96SW2 1/20 0.35
TSHR P16473 3/20 0.33
GAA P10253 2/20 0.33
MGAM O43451 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Carbamate SCHEMBL28423961 0.85 MEN1 (0.39) NQO1ALDH1A1ALOX15PMP22LMNA
Methyl Carbamate SCHEMBL28142916 0.81
Acetamide SCHEMBL25171190 0.81 LMNA (0.61) NQO1ALDH1A1ALOX15PMP22LMNA
Urea SCHEMBL9838387 0.81 LMNA (0.50) NQO1ALDH1A1ALOX15PMP22LMNA
Methyl Carbamate SCHEMBL788713 0.80 ALDH1A1 (0.50) NQO1ALDH1A1ALOX15PMP22LMNA
Methyl Carbamate SCHEMBL4140 0.80
SCHEMBL10414882 0.79 ALDH1A1 (0.41) NQO1ALDH1A1ALOX15PMP22LMNA
Carbamic Acid SCHEMBL18889456 0.78 ACHE (0.50) NQO1ALDH1A1ALOX15PMP22LMNA
Methyl Carbamate SCHEMBL50681 0.78
Methyl Carbamate SCHEMBL3465246 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4472521-A TITANIUM ALKOXIDE, MANGANESE OR MAGNESIUM ALKOXIDE, HALOGENATION STAUFFER CHEMICAL COMPANY (US) 1984-09-18 US disclosed
EP-0113937-A1 Supported catalyst for polymerization of olefins STAUFFER CHEMICAL COMPANY (US) 1984-07-25 EP disclosed