Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17289237 | 0.85 | ALDH1A1 (0.46) | SMN1; SMN2NPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL9301199 | 0.83 | KMT2A (0.41) | HTTPOLBNPC1ALDH1A1MAPT | |
| SCHEMBL9714149 | 0.83 | POLB (0.45) | SMN1; SMN2POLBALDH1A1MAPTLMNA | |
| SCHEMBL11041660 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2HTTPOLBNPC1ALDH1A1 | |
| SCHEMBL16868449 | 0.74 | NPSR1 (0.51) | SMN1; SMN2POLBNPC1MAPTLMNA | |
| SCHEMBL28422094 | 0.74 | CES2 (0.46) | ALDH1A1KDM4EMAPTLMNAL3MBTL1 | |
| SCHEMBL11515099 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2HTTPOLBALDH1A1KDM4E | |
| SCHEMBL914714 | 0.72 | NPC1 (0.48) | SMN1; SMN2POLBNPC1ALDH1A1MAPT | |
| SCHEMBL11044692 | 0.71 | NR1I2 (0.46) | POLBNPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL914602 | 0.70 | PPARD (0.42) | SMN1; SMN2HTTPOLBNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9493494-B2 | Phosphinine oxide derivative and preparation method thereof | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2016-11-15 | — | — | US | disclosed |
| US-20150344506-A1 | NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF | KNU-INDUSTRY COOPERATION FOUNDATION (KR) | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344506-A1 | NOVEL PHOSPHININE OXIDE DERIVATIVE AND PREPARATION METHOD THEREOF | PHOSPHO1, PPIP5K2, ITPA | SMN1; SMN2 4065/4885HTT 4448/4885POLB 2599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.