Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.57 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065378 | 0.91 | PLA2G2A (0.56) | PLA2G2ACACNA2D1LMNAS1PR1P2RX7 | |
| SCHEMBL11065373 | 0.85 | PLA2G2A (0.55) | PLA2G2ALMNAS1PR1P2RX7TP53 | |
| SCHEMBL11045671 | 0.84 | PLA2G2A (0.56) | PLA2G2ALMNAHPGDRAB9A | |
| SCHEMBL11047702 | 0.82 | PLA2G2A (0.60) | PLA2G2ALMNAS1PR1P2RX7 | |
| SCHEMBL11051562 | 0.82 | PLA2G2A (0.54) | PLA2G2ALMNAS1PR1NPC1RAB9A | |
| SCHEMBL11047681 | 0.81 | PLA2G2A (0.56) | PLA2G2ALMNAS1PR1P2RX7TP53 | |
| SCHEMBL11047743 | 0.81 | PLA2G2A (0.53) | PLA2G2ACACNA2D1S1PR1 | |
| SCHEMBL11045600 | 0.78 | PLA2G2A (0.56) | PLA2G2ALMNANPC1RAB9AACHE | |
| SCHEMBL11047656 | 0.77 | PLA2G2A (0.50) | PLA2G2AHPGD | |
| SCHEMBL11049739 | 0.76 | PLA2G2A (0.54) | PLA2G2ALMNAS1PR1P2RX7TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477666-A | ANTICARCINO GENIC AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4477664-A | CARCINOSTATIC ACTIVITY, LOW TOXICITY, INTERMEDIATES | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4460774-A | ANTICARCINOGENIC AGENTS | TOYAMA CHEMICAL COMPANY, LIMITED (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4459407-A | ANTICARCINOGENIC | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-07-10 | — | — | US | disclosed |
| US-4448963-A | ANTICARCINOGENS | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-05-15 | — | — | US | disclosed |
| US-4436921-A | CARCINOSTATIC ACTIVITY | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-03-13 | — | — | US | disclosed |