Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 6/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043677 | 0.83 | ALDH1A1 (0.52) | LMNAP2RX7 | |
| SCHEMBL11044784 | 0.82 | PLA2G2A (0.57) | PLA2G2ALMNAS1PR1P2RX7 | |
| SCHEMBL11065378 | 0.81 | PLA2G2A (0.56) | PLA2G2ALMNAS1PR1P2RX7 | |
| SCHEMBL11045600 | 0.81 | PLA2G2A (0.56) | PLA2G2ALMNA | |
| SCHEMBL11065373 | 0.80 | PLA2G2A (0.55) | PLA2G2ALMNAS1PR1P2RX7 | |
| SCHEMBL11051562 | 0.80 | PLA2G2A (0.54) | PLA2G2ALMNAS1PR1 | |
| SCHEMBL11049739 | 0.79 | PLA2G2A (0.54) | PLA2G2ALMNAS1PR1P2RX7 | |
| SCHEMBL11045671 | 0.79 | PLA2G2A (0.56) | PLA2G2ALMNA | |
| SCHEMBL11045628 | 0.77 | L3MBTL1 (0.51) | P2RX7 | |
| SCHEMBL11047743 | 0.76 | PLA2G2A (0.53) | PLA2G2AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477664-A | CARCINOSTATIC ACTIVITY, LOW TOXICITY, INTERMEDIATES | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4477666-A | ANTICARCINO GENIC AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4460774-A | ANTICARCINOGENIC AGENTS | TOYAMA CHEMICAL COMPANY, LIMITED (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4448963-A | ANTICARCINOGENS | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-05-15 | — | — | US | disclosed |
| US-4436921-A | CARCINOSTATIC ACTIVITY | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-03-13 | — | — | US | disclosed |