Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044784 | 0.85 | PLA2G2A (0.57) | PLA2G2ATP53LMNAS1PR1P2RX7 | |
| SCHEMBL11045671 | 0.84 | PLA2G2A (0.56) | PLA2G2ALMNAPOLBHPGDRAB9A | |
| SCHEMBL11065378 | 0.84 | PLA2G2A (0.56) | PLA2G2ATP53LMNAS1PR1P2RX7 | |
| SCHEMBL11047702 | 0.80 | PLA2G2A (0.60) | PLA2G2ALMNAS1PR1P2RX7 | |
| SCHEMBL11051562 | 0.80 | PLA2G2A (0.54) | PLA2G2ALMNAS1PR1POLBSPHK1 | |
| SCHEMBL11047743 | 0.79 | PLA2G2A (0.53) | PLA2G2AS1PR1 | |
| SCHEMBL11047681 | 0.79 | PLA2G2A (0.56) | PLA2G2ATP53LMNAS1PR1P2RX7 | |
| SCHEMBL11045600 | 0.76 | PLA2G2A (0.56) | PLA2G2ALMNANPC1RAB9A | |
| SCHEMBL11047656 | 0.75 | PLA2G2A (0.50) | PLA2G2AHPGD | |
| SCHEMBL11049739 | 0.74 | PLA2G2A (0.54) | PLA2G2ATP53LMNAS1PR1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477666-A | ANTICARCINO GENIC AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | claimed |