SCHEMBL11044912

SCHEMBL11044912

O=NN1CC([N+](=O)[O-])([N+](=O)[O-])CN(N=O)CC([N+](=O)[O-])([N+](=O)[O-])C1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.31
CRHBP P24387 1/20 0.30
CRHR2 Q13324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11043914 0.89
SCHEMBL11048898 0.85
Nitric Acid SCHEMBL11044841 0.80
SCHEMBL7248680 0.69 GAA (0.33) GAACRHBPCRHR2
SCHEMBL436830 0.69 GAA (0.33) GAACRHBPCRHR2
SCHEMBL9921596 0.69 GAA (0.38) GAACRHBPCRHR2
SCHEMBL11230841 0.65 GAA (0.35) GAACRHBPCRHR2
SCHEMBL29265156 0.65 CRHBP (0.34) GAACRHBPCRHR2
SCHEMBL17484752 0.63 ALDH1A1 (0.41) GAACRHBPCRHR2
SCHEMBL1994684 0.63 CRHBP (0.63) GAACRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4452739-A 1,3,3,5,7,7-Hexanitroperhydro-1,5-diazocine, N-nitroso analogs thereof, and processes for their preparation THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1984-06-05 US claimed
US-4452739-A 1,3,3,5,7,7-Hexanitroperhydro-1,5-diazocine, N-nitroso analogs thereof, and processes for their preparation THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1984-06-05 US disclosed