Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436830 | 1.00 | GAA (0.33) | GAACRHBPCRHR2NLRP3 | |
| SCHEMBL11230841 | 0.90 | GAA (0.35) | GAACRHBPCRHR2 | |
| SCHEMBL11043914 | 0.85 | — | — | |
| SCHEMBL7254408 | 0.85 | — | — | |
| SCHEMBL13613326 | 0.74 | APEX1 (0.43) | GAACRHBPCRHR2 | |
| SCHEMBL9921596 | 0.72 | GAA (0.38) | GAACRHBPCRHR2NLRP3 | |
| SCHEMBL2348600 | 0.72 | GAA (0.30) | GAA | |
| SCHEMBL11044912 | 0.69 | GAA (0.31) | GAACRHBPCRHR2 | |
| SCHEMBL29265156 | 0.69 | CRHBP (0.34) | GAACRHBPCRHR2 | |
| SCHEMBL17484752 | 0.67 | ALDH1A1 (0.41) | GAACRHBPCRHR2NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452739-A | 1,3,3,5,7,7-Hexanitroperhydro-1,5-diazocine, N-nitroso analogs thereof, and processes for their preparation | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1984-06-05 | — | — | US | claimed |
| CN-117707017-A | Coal mine fully-mechanized coal mining equipment control system based on Web data interaction | 天津华宁电子有限公司 | 2024-03-15 | — | — | CN | disclosed |
| US-6562985-B2 | Geminal-dinitro-1-5 diazocine derivatives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2003-05-13 | — | — | US | disclosed |
| US-20020161248-A1 | Geminal-dinitro-1-5 diazocine derivatives | CHAPMAN ROBERT DALE (US) | 2002-10-31 | — | — | US | disclosed |
| US-6417355-B1 | EXPLOSIVES, PROPELLANT OXIDIZERS; FLUOROAMINATION, NITRATION, SULFONYLATION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY | 2002-07-09 | — | — | US | disclosed |
| US-4452739-A | 1,3,3,5,7,7-Hexanitroperhydro-1,5-diazocine, N-nitroso analogs thereof, and processes for their preparation | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1984-06-05 | — | — | US | disclosed |
| US-4452739-A | 1,3,3,5,7,7-Hexanitroperhydro-1,5-diazocine, N-nitroso analogs thereof, and processes for their preparation | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1984-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161248-A1 | Geminal-dinitro-1-5 diazocine derivatives | TNF, TNFRSF1A, AOX1 | GAA 874/4885CRHBP 4870/4885CRHR2 4487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.