Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.34 |
| ▸ | FBP1 | P09467 | 2/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044915 | 1.00 | APP (0.52) | APPENPP2TRPV1NFE2L2FBP1 | |
| SCHEMBL698580 | 0.80 | APP (0.72) | APPNFE2L2CYP19A1MAOAMAOB | |
| SCHEMBL698579 | 0.80 | APP (0.72) | APPNFE2L2CYP19A1MAOAMAOB | |
| SCHEMBL11039441 | 0.76 | HSD17B3 (0.56) | HSD17B3MAOAMAOBNPSR1 | |
| SCHEMBL2319724 | 0.76 | NFE2L2 (0.65) | APPNFE2L2FBP1CYP1A2MAOA | |
| SCHEMBL2319722 | 0.76 | NFE2L2 (0.65) | APPNFE2L2FBP1CYP1A2MAOA | |
| SCHEMBL2348351 | 0.76 | LCK (0.59) | FBP1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL2348347 | 0.76 | LCK (0.59) | FBP1CCNB2CDK1CDK4CCNB1 | |
| SCHEMBL2345287 | 0.76 | FBP1 (0.53) | NFE2L2FBP1CYP1A2MAOAMAOB | |
| SCHEMBL2349000 | 0.76 | CYP1A2 (0.56) | NFE2L2FBP1CYP1A2CYP2C9MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |