Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350237 | 0.92 | MAOB (0.55) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| SCHEMBL9124972 | 0.92 | NR3C1 (0.66) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL7293032 | 0.90 | MAOB (0.54) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11047745 | 0.89 | ALDH1A1 (0.64) | ALDH1A1TSHRSMN1; SMN2LMNAKMT2A | |
| SCHEMBL11197452 | 0.85 | ALDH1A1 (0.60) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL11041952 | 0.85 | DRD2 (0.65) | ALDH1A1HSD17B10CRBNTSHRNR3C1 | |
| SCHEMBL11046347 | 0.83 | NR3C1 (0.62) | ALDH1A1HPGDCRBNTSHRNR3C1 | |
| SCHEMBL11045054 | 0.82 | CRBN (0.62) | ALDH1A1HPGDCRBNGAANR3C1 | |
| SCHEMBL7325238 | 0.82 | CRBN (0.58) | ALDH1A1HPGDCRBNNR3C1PGR | |
| Iodide SCHEMBL11041065 | 0.82 | NR3C1 (0.61) | ALDH1A1HPGDCRBNTSHRNR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |